About Us
We are a group of experimental cell biologists with the longterm goal of understanding how cell cycle control is interfaced with other essential cellular functions. Our current projects seek to address how cell size affects cell cycle progression and DNA damage signaling in mammalian cells.
Questions that we find fascinating include:
How do cells sense their own size and convey that information to the cell cycle regulation apparatus?
How do size-related changes in cell physiology affect genome homeostasis?
What processes have “input” into the cell cycle machine?
Approaches
We thrive at integrating functional genomics tools (proteomics, transcriptomics, and spatial genomics) with classical cell biology approaches to ask and answer mechanistic questions about what regulates cell division.
Collaborators
We have active collaborations with:
the Silva lab (Duke University)
the Schmoller lab (LMU Munich)
the Belmont lab (University of Illiniois, Urbana Champaign)
the Neurohr lab (ETH Zurich)
